Blastomyces dermatitidis is a dimorphic fungus that typically causes disease in immunocompromised hosts, but can affect immunocompetent patients as well. Here we present a case of disseminated blastomycosis in a pregnant patient at 11 weeks gestation who was successfully treated with systemic antifungal therapy. Data regarding treatment of blastomycosis in pregnancy is limited, and choice of antifungal agent remains challenging due to uncertainties regarding fetal toxicity.
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